Yuki Hatoyama

The paper measures local nucleosome motion in living human cells during interphase and finds it remains nearly constant, with changes observed under specific perturbations.

This study shows MCM10 and RECQL4 work together and can replace each other in activating the CMG helicase during DNA replication initiation.

The paper shows that XRN2-dependent decay of mG-hypomodified tRNAs occurs under physiological conditions and is conserved across species.

This paper develops a scAb-AID2 system for conditional protein degradation without requiring degron tags, demonstrating its effectiveness in human and C. elegans cells.

The paper combines AID2 and BromoTag degron systems to enhance protein depletion, demonstrating their effectiveness in suppressing DNA replication by co-depleting ORC1 and CDC6.