Carmen Amador

Phenome-wide analysis identifies parent-of-origin effects on the human methylome associated with changes in the rate of aging

The paper identifies parent-of-origin effects on the methylome linked to aging rates by analyzing CpG methylation in a large family cohort.

Genome-by-Trauma Interaction Effects in Depression

This study examines genome-by-trauma interaction effects on depression using whole genome data and finds significant variance explained by these interactions, particularly in males.

Lifestyle and Genetic Factors Modify Parent-of-Origin Effects on the Human Methylome

This study identifies modifiable parent-of-origin effects on DNA methylation by analyzing genetic and environmental factors in a large cohort.

Methylome-wide association study of early life stressors and adult mental health reveals a relationship between birth date and cell type composition in blood

This study investigates the relationship between early life stressors and adult mental health through methylome-wide association studies, finding no evidence of methylome mediation but linking birth date to blood cell type composition.

Genome-wide methylation data improves dissection of the effect of smoking on body mass index.

This study uses genome-wide methylation data to assess the impact of smoking and gene-smoking interactions on obesity-related traits, showing improved variance explanation compared to traditional methods.

Identification of epigenome-wide DNA methylation differences between carriers of APOE ϵ4 and APOE ϵ2

This study identifies epigenome-wide DNA methylation differences between APOE ε4 and ε2 carriers in whole blood, implicating lipid-related genes.

Proteome-by-phenome Mendelian Randomisation detects 38 proteins with causal roles in human diseases and traits

Epigenome-wide analyses identify DNA methylation signatures of dementia risk

The paper identifies DNA methylation signatures associated with dementia risk factors in blood samples from individuals without Alzheimer's disease.

Genetic and environmental determinants of stressful life events and their overlap with depression and neuroticism

The paper investigates the genetic and environmental contributions to stressful life events and their overlap with depression and neuroticism using a large family-based sample.

Genomic analysis of family data reveals additional genetic effects on intelligence and personality

The paper uses family data to estimate genetic effects on intelligence and personality, finding that rare variants explain more variance than previously reported using unrelated individuals.

Shared genetics and couple-associated environment are major contributors to the risk of both clinical and self-declared depression

This study identifies shared genetic and couple-associated environmental factors contributing to both clinical and self-declared depression risks.