Jonathan Wilson Yewdell

The paper investigates how mutations in SARS-CoV-2 N protein affect RNP formation and stability, finding convergent evolution and enhanced RNP assembly in Omicron variants.

This study investigates how vaccine antigen valency and pre-existing memory B cells influence B cell responses to drifted influenza virus, showing differential effects on germinal center dynamics and immunodominance.

This paper uses advanced microscopy to show that SARS-CoV-2 attaches to and enters cells via heparan sulfate clusters, not ACE2, and that blocking HS binding inhibits viral infection.

This study identifies antibody avidity as a correlate for in vivo efficacy of broadly reactive anti-alphavirus antibodies and links it to Fc-dependent mechanisms.

This study identifies a two-step mechanism by which influenza virus mini viral RNAs (mvRNAs) activate RIG-I through non-canonical transcription and RNA structure-dependent binding.

This study shows that pre-existing antibodies inhibit de novo B cell responses to influenza antigens in mice, but not to other vaccine antigens.

The paper uses RNA GUESS to identify conserved RNA structures in enterovirus 71, revealing novel structural elements with potential functional roles.

The paper introduces a computational method to identify conserved RNA structures in influenza A virus mRNAs, revealing previously unknown structured regions critical for viral replication.