Markus Lakemeyer

This study shows how ambient temperature changes affect cellular responses in Chlamydomonas reinhardtii, revealing extensive transcriptomic and proteomic changes linked to growth, cilia behavior, and bacterial interactions.

This paper introduces covalent macrocyclic activity-based probes (cmABPs) that selectively target non-catalytic residues in serine proteases, demonstrating their effectiveness with plasma kallikrein and urokinase plasminogen activator.

This study shows that fluorination of inhibitors can tune protein dimerization affinity by altering enzyme-inhibitor interactions and dynamics.

This study identifies a secreted protease from Bacteroides fragilis that cleaves PAR2, leading to intestinal inflammation and pain in mouse models.