Hélène Munier‐Lehmann

The paper characterizes the regulatory mechanism of class II bacterial IMPDH from Burkholderia thailandensis, showing MgGTP's dual role in enzyme activity and oligomerization.

This paper identifies small molecules that inhibit the SARS-CoV-2 E protein interaction with ZO-1 PDZ2 using X-ray crystallography, HTRF screening, and docking simulations, with one compound showing antiviral activity.

This study investigates the structural and functional organization of the de novo purine nucleotide biosynthetic pathway enzymes in Pseudomonas aeruginosa, revealing a metabolon-like complex with potential antibiotic implications.