Author

Vera D. Kovaleva

University of HelsinkiORCID 0000-0001-7597-0480Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 3

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Organism:human· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

Märt SaarmaiD· 3 shared Li-Ying YuiD· 2 shared Mati M. KarelsoniD· 2 shared Anna SteinzeigiD· 1 shared Caroline BiojoneiD· 1 shared Cassiano R.A.F. DiniziD· 1 shared Cecilia Anna BrunelloiD· 1 shared Cecilia CannarozzoiD· 1 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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3 shared papersNeuroscience

Märt SaarmaORCID

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3 papers

Recent·Most cited

NeurosciencebioRxivPreprintDec 17, 2024

CDNF rescues human iPSCs-derived dopamine neurons through direct binding to unfolded protein response sensors PERK and IRE1α

Vera D. Kovaleva, Olesya G. Shpironok, Li-Ying Yu…·Märt Saarma

This study identifies CDNF's mechanism of action by showing it rescues human dopamine neurons through direct binding to UPR sensors PERK and IRE1α.

2 citations

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NeuroscienceInternational Journal of Molecular SciencesPeer-reviewedApr 26, 2021

Small-molecule inhibitors of the RNA m6A demethylase FTO potently support the survival of dopamine neurons

Simona Selberg, Li-Ying Yu, Olesja M. Bondarenko…·Mati M. Karelson

This study develops small-molecule FTO inhibitors that enhance dopamine neuron survival and show BBB penetration, with greater potency than existing AlkBH5 inhibitors.

52 citations

mousemachine learning (classical)

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NeuroscienceCellPeer-reviewedFeb 18, 2021

Antidepressant drugs act by directly binding to TRKB neurotrophin receptors

Plinio Cabrera Casarotto, Mykhailo Girych, Senem Merve Fred…·Eero Ċastrén

This study identifies a direct binding of antidepressants to TRKB receptors, revealing a mechanism linking molecular interactions to antidepressant effects.

662 citationstop 1%

humanproteomics

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