Sonja E. Di Gregorio

This study compares soluble α-synuclein species from MSA and LBD brains, finding differences in their seeding activity and size distribution.

This study shows TUDCA reduces drug bioavailability, not directly aiding protein folding, and rescues yeast from ER stress by sequestering toxic compounds.

The paper establishes a yeast model of Matrin3, showing it forms inclusions and is toxic, and identifies Hsp90 and Sti1 as modifiers of its misfolding and toxicity.