Author

Jordan T. Becker

University of MinnesotaORCID 0000-0002-0239-5443Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 2 Genetics· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Organism:chicken / avian· 2 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Clayton K. MickelsoniD· 3 shared Lauren M. ProssiD· 3 shared Ryan Andrew LangloisiD· 3 shared Alison J. BarkhymeriD· 2 shared Frances K. ShepherdiD· 2 shared Mark SalnikoviD· 2 shared Adam J. GilbertseniD· 1 shared Anja‐Katrin BielinskyiD· 1 shared

Activity by Year

2022-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersMicrobiology

Clayton K. MickelsonORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

A mammalian fibroblast zoo reveals barriers to cross-species virus replication and differential regulation of antiviral immunity

Clayton K. Mickelson, Mark Salnikov, Frances K. Shepherd, Lauren M. Pross, Georgia McClain, Swechha Mainali Pokharel, H. Heinrich Hoffmann, Timo Schoon, Girish Pulinkala, Nakarin Pamornchainavakul, Kayla Hoffman, Cera A. McDonald, Esther Vogt, Tristan T. Neal, Adam J. Gilbertsen, , Ryan A. Langlois

The paper uses fibroblasts from 86 mammalian species to study virus-host susceptibility and innate immune responses across diverse mammals.

bioRxiv · Nov 6, 2026 · PreprintImmunology

A chicken interferon stimulated gene screen reveals limited genes restricting influenza replication

Alison J. Barkhymer, Jordan T. Becker, Frances Shepherd, Clayton K. Mickelson, Lauren M. Pross, Mark Salnikov, Ryan Andrew Langlois

This study identifies interferon-stimulated genes (ISGs) in chicken, quail, and duck cells and performs a CRISPR knockout screen to find genes restricting influenza replication, revealing species-specific differences in antiviral immunity.

bioRxiv · Jul 24, 2026 · PreprintMicrobiology

Mammalian ZAP and KHNYN can independently restrict CpG-enriched avian viruses

Jordan T. Becker, Clayton K. Mickelson, Lauren M. Pross, Autumn E. Sanders, Esther R. Vogt, Frances K. Shepherd, Chloe Wick, Alison J. Barkhymer, Stephanie L. Aron, Elizabeth J. Fay, Reuben S. Harris, Ryan Andrew Langlois

The paper shows mammalian ZAP and KHNYN can restrict CpG-enriched avian viruses, with human ZAP or KHNYN independently limiting CpG-enriched IAV in chicken and human cells.

PLoS Biology · Oct 28, 2025Peer-reviewedMicrobiology

Msh2-Msh3 interferes with DNA metabolism in vivo

Melisa Medina‐Rivera, Samantha Phelps, Madhumita Sridharan, Jordan T. Becker, Natalie A. Lamb, Charanya Kumar, Mark D. Sutton, Anja‐Katrin Bielinsky, Lata Balakrishnan, Jennifer A. Surtees

This study shows that elevated Msh2-Msh3 levels interfere with DNA replication and long-patch base excision repair in vivo, contributing to genomic instability.

bioRxiv · Sep 6, 2022 · PreprintGenetics