Asim S. Siddiqui

Deep Profiling of Plasma Proteoforms with Engineered Nanoparticles for Top-down Proteomics

This study uses engineered nanoparticles to enrich low-abundant proteins in human plasma, enabling top-down proteomics to detect proteoforms at lower concentrations and expand proteome depth.

Nanoparticle Enrichment Mass-Spectrometry Proteomics Identifies Protein Altering Variants for Precise pQTL Mapping

This study uses mass spectrometry proteomics to identify protein altering variants and map pQTLs, confirming target specificity and identifying novel variants not accessible by affinity proteomics.

Identification of Novel Biomarkers for Alzheimer's Disease and Related Dementias Using Unbiased Plasma Proteomics

This study identifies novel plasma biomarkers for Alzheimer's disease and related dementias using unbiased proteomics in a large cohort.

Single Cell RNA-seq reveals ectopic and aberrant lung resident cell populations in Idiopathic Pulmonary Fibrosis

This study uses single-cell RNA-seq to identify aberrant cell populations in IPF lungs, revealing novel basaloid cells and vascular endothelial changes.