Author

Inés María García-Pérez

Institute for Research in BiomedicineORCID 0000-0002-0737-9151Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Approach:genetic perturbation / CRISPR· 1 Assay:proteomics· 1

Frequent Co-Authors

Cristina Mayor‐RuiziD· 2 shared Alberto MartíniD· 1 shared Alberto VillanuevaiD· 1 shared Ana DomosteguiiD· 1 shared Antoni RiéraiD· 1 shared Bárbara M. G. BarbosaiD· 1 shared Camille Stephan‐Otto AttoliniiD· 1 shared Carlos Riego‐MejíasiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersCancer Biology

Cristina Mayor‐RuizORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

RAF1 scaffold integrity shapes chemogenetic degradation outcomes in KRAS-driven lung cancer

Laura de la Puente Ovejero, Ana Domostegui, Inés María García-Pérez, Gonzalo Aizpurua, Lucia Lomba-Riego, Pilar Ximénez‐Embún, Cristina Mayor‐Ruiz, Mariano Barbacid, Sara García‐Alonso

This study shows that chemogenetic degradation of RAF1 in KRAS-driven lung cancer does not replicate genetic ablation outcomes due to scaffold disruption.

bioRxiv · Jul 6, 2026 · PreprintCancer Biology

Targeted KRAS(G12V) degradation elicits efficient and durable lung adenocarcinoma regression in vivo

Alberto Martín, Inés María García-Pérez, Sonia San José, Pep Rojo, Carlos Riego‐Mejías, Cristina Teodósio, Bárbara M. G. Barbosa, Carolina Sánchez, Ignasi Folch-I-Casanovas, María Antonia Odena, Sònia Jarió, Sara Hijazo‐Pechero, Silvia M. Rodríguez-López, Rodrigo Entrialgo‐Cadierno, Marie‐Julie Nokin, , Cristina Mayor‐Ruiz

This study shows that targeted KRAS(G12V) degradation causes durable lung adenocarcinoma regression in mice, with tumor relapse linked to proteolysis machinery dysregulation.

Cancer Research · May 27, 2026Peer-reviewedCancer Biology