Author

Valentin Magidson

Frederick National Laboratory for Cancer ResearchORCID 0000-0002-0780-9123Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:development & morphogenesis· 2 Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Abhi Senthilkumar· 1 shared Adam HarnediD· 1 shared Ajit Kumar SharmaiD· 1 shared Anish ThomasiD· 1 shared Anjali DhalliD· 1 shared Avaneesh Kilnagar· 1 shared Beverly A. TeicheriD· 1 shared Chiori TabeiD· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCell Biology

Abhi Senthilkumar

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3 papers

Recent·Most cited

Characterization of membrane structures regulating primary ciliogenesis by quantitative isotropic ultrastructure imaging

Quanlong Lü, Huijie Zhao, Ziam Khan, Adam Harned, Erina Kamiya, Valentin Magidson, Abhi Senthilkumar, Avaneesh Kilnagar, Phuong Thi Bich Doan, Sumeth Perera, Kedar Narayan, Christopher J. Westlake

This study identifies key membrane structures and proteins involved in primary ciliogenesis using isotropic ultrastructure imaging and 3D analysis.

Nature Communications · Jun 13, 2026Peer-reviewedCell Biology

Lamin A/C Deficiency Drives Genomic Instability and Poor Survival in Small-Cell Lung Cancer through Increased R-loop Accumulation

Christopher William Schultz, Sourav Taru Saha, Anjali Dhall, Yang Zhang, Parth Anil Desai, Lőrinc Sándor Pongor, David A. Scheiblin, Valentin Magidson, Yilun Sun, Christophe E. Redon, Suresh Kumar, Manan Krishnamurthy, Henrique Bregolin Dias, Vasilisa Aksenova, Elizabeth G Giordano, , Anish Thomas

This study shows that LMNA deficiency in SCLC increases R-loop accumulation, leading to genomic instability and poor patient survival.

bioRxiv · Apr 29, 2025 · PreprintCancer Biology

Fgf4 is critical for maintaining Hes7 levels and Notch oscillations in the somite segmentation clock

Matthew J. Anderson, Valentin Magidson, Ryoichiro Kageyama, Mark B. Lewandoski

This study shows Fgf4 is essential for maintaining Hes7 levels and Notch oscillations in the somite segmentation clock, leading to vertebral defects in Fgf4 mutants.

eLife · Nov 19, 2020Peer-reviewedDevelopmental Biology