Momchil Ninov

Nanobinders for Synaptotagmin 1 enable the analysis of synapticvesicle dynamics in rodent and human models.

The paper introduces NbLumSyt1 nanobinders for analyzing synaptic vesicle dynamics in rodent and human models with improved precision and versatility.

Conserved reduction of m6A marks during aging and neurodegeneration is linked to altered translation of synaptic transcripts

The paper examines m6A RNA methylation changes in mouse and human brains during aging and Alzheimer's disease, finding reduced m6A levels in synaptic transcripts and impaired synaptic protein synthesis.

Co-localization of different neurotransmitter transporters on synaptic vesicles is sparse except of VGLUT1 and ZnT3

The paper shows that a small population of synaptic vesicles contain different neurotransmitter transporters, enabling corelease of various neurotransmitter combinations.

The Coding And Small-Non-Coding Hippocampal Synaptic RNAome

The paper isolates synaptic RNA from hippocampal neurons and identifies microRNAs that regulate the synaptic mRNAome, suggesting astrocytic contribution and dynamic regulation.