Armando G. Salinas

Selective impairment of long-term depression in accumbal D1R+ MSNs involves calcium-permeable AMPARs in early Alzheimer's disease

This study identifies a cell-type-specific synaptic mechanism in the nucleus accumbens linking early Aβ accumulation to circuit dysfunction in early Alzheimer's disease.

Chronic ethanol self-administration alters dopamine in the caudate nucleus and putamen of rhesus macaques in a sex-dependent manner

This study shows chronic ethanol self-administration in rhesus macaques alters dopamine signaling in the caudate and putamen, with sex-specific differences in release and uptake.

External Globus Pallidus Arkypallidal Circuit Dynamics Gate Risk-Taking Behavior

The paper identifies a circuit mechanism in the globus pallidus externa that regulates risk-taking behavior through specific neuronal activity.

Ethanol inhibits dorsomedial striatum acetylcholine release

This study shows that ethanol inhibits acetylcholine release in the dorsomedial striatum, potentially contributing to AUD-related behaviors.

Ketone ester-enriched diet ameliorates motor and dopamine release deficits in MitoPark mice

This study shows that a ketone ester-enriched diet improves motor function and dopamine release in MitoPark mice with Parkinson's disease-like symptoms.

Sub-second striatal dopamine dynamics assessed by simultaneous fast-scan cyclic voltammetry and fluorescence biosensor

The paper evaluates dLight photometry for measuring dopamine dynamics in the dorsolateral striatum, showing it can detect dopamine increases and transient kinetics during cocaine exposure and conditioning.

Deficiency in endocannabinoid synthase DAGLB contributes to Parkinson's disease and dopaminergic neuron dysfunction

This study shows that deficiency in DAGLB, an endocannabinoid synthase, contributes to Parkinson's disease by impairing dopaminergic neuron function and motor learning, with potential therapeutic implications for 2-AG augmentation.