Author

Trevor G. Shepherd

Western UniversityORCID 0000-0002-1853-8066Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:cancer & tumor microenvironment· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

Andrew W. CraigiD· 1 shared Anne-Marie Mes Masson· 1 shared Anne-Marie Mes-Masson· 1 shared Athena Southworth· 1 shared Basile Tessier Cloutier· 1 shared Cédric DjoumessiiD· 1 shared Céline DomecqiD· 1 shared Chad Kelawan· 1 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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1 shared paperBiochemistry

Andrew W. CraigORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Tumour architecture shapes polarized epithelial states that predict survival in high-grade serous ovarian cancer

Sarah Nersesian, John Abou‐Hamad, Emma Durocher, Gaëlle Akiki, Céline Domecq, Athena Southworth, Katrina N. Verey, Hugh H. Deng, Yudith Ramos-Valdes, Liliane Meunier, Manon de Ladurantaye, Trevor G. Shepherd, Anne-Marie Mes Masson, Anne-Marie Mes-Masson, Basile Tessier Cloutier, David P. Cook

The paper identifies a polarization axis in ovarian cancer cells linked to tumor architecture and survival, showing SecB cells correlate with poor prognosis and metastasis.

bioRxiv · Oct 22, 2026 · PreprintCancer Biology

WNT8B and -9B promote the survival and dissemination of dormant ovarian cancer cells

Komila Zakirova, Daniel T. Passos, Chad Kelawan, Michael V. Roes, Rizwan Tahir, Malcolm Hill, Seung J. Kim, Matthew J. Cecchini, Marco Mura, Trevor G. Shepherd, Pirunthan Perampalam, James I. MacDonald, Frederick A. Dick

This study identifies WNT8B and WNT9B as critical for ovarian cancer cell survival and dissemination during dormancy, showing their inhibition could improve treatment outcomes.

bioRxiv · Aug 11, 2026 · PreprintCancer Biology

Isolation of Extracellular Vesicles from Minimal Volume Ascites Fluid Using Strong Anion Exchange Magnetic Beads

Tyler T. Cooper, Lorena Veliz, Farzaneh Afzali, Cédric Djoumessi, Owen F.J. Hovey, Robert L. Myette, Tiffany P. A. Johnston, Chris Wells, Tristan Robertson, Dylan E Burger, Sheela A. Abraham, Trevor G. Shepherd, Andrew W. Craig, François Lagugné‐Labarthet, Gilles A. Lajoie, Lynne-Marie M Postovit

This study isolates extracellular vesicles from minimal ascites fluid using strong anion exchange magnetic beads, enhancing proteomic depth and identifying new proteins and SERS signatures in ovarian cancer-derived EVs.

Nanoscale Advances · Jan 1, 2026Peer-reviewedBiochemistry