Christine Viaris de Lesegno

The paper shows that palmitoylated caveolin-1 facilitates endosome sorting of complex sphingolipids to the plasma membrane, independent of caveolae.

This study shows mechanical stress increases EV release from cancer cells via caveolin-1, leading to more tumorigenic EVs that promote metastasis.

This study identifies STAM interaction with Hrs as critical for IFN-α-induced JAK/STAT activation at the early endosome, revealing endosomal sorting's role in differential signaling.

This study shows that Cav3 mutations in human dystrophic myotubes impair caveolae function, leading to defective mechanoprotection and aberrant IL6/STAT3 signaling.