Analı́a A Bortolozzi

A molecular convergence in the triad of Parkinson's disease, depressive disorder and gut health is revealed by the inflammation-miRNA axis

This study identifies a shared miRNA-inflammatory axis linking Parkinson's disease, depressive disorder, and gut dysfunction through molecular convergence in human and mouse models.

Early synaptic changes and reduced brain connectivity in PD-like mice with depressive phenotype

The paper investigates synaptic changes and brain connectivity in a PD-like mouse model with depressive symptoms, finding early synaptic markers linked to -synuclein pathology.

Modelling human neuronal catecholaminergic pigmentation in rodents recapitulates age-related multisystem neurodegenerative deficits

This paper creates a transgenic mouse model that mimics human neuromelanin accumulation in catecholaminergic neurons, leading to age-related neurodegenerative deficits.

iPSC-based modeling of THD recapitulates disease phenotypes and reveals neuronal malformation

This study uses iPSC-derived dopaminergic neurons to model THD, showing disease-specific phenotypes and treatment responses.