Author

Lei Qu

Anhui UniversityORCID 0000-0002-2129-5253Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:mouse· 3 Research Focus:benchmarking· 2 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Assay:imaging· 2 Assay:spatial transcriptomics· 2 Approach:statistical model· 2 Approach:benchmark study· 1

Frequent Co-Authors

Hanchuan PengiD· 3 shared Hongkui ZengiD· 3 shared Michael HawrylycziD· 3 shared Christof Koch AiD· 2 shared Giorgio A. AscoliiD· 2 shared Lydia NgiD· 2 shared Quanxin WangiD· 2 shared Shengdian JiangiD· 2 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersBioinformatics

Hanchuan PengORCID

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Author profile →

4 papers

Recent·Most cited

High-speed mapping of whole-mouse peripheral nerves at subcellular resolution

Mei-Yu Shi, Yuchen Yao, Miao Wang, Qi Yang, Lufeng Ding, Rui Li, Yuanyuan Li, Haimeng Huang, Chaoyu Yang, Zhao Zhou, Zhenxiang Zhu, Pengjie Wen, Fangling Dai, Xiaohui Zeng, Keming Zhang, , Guo‐Qiang Bi

This paper presents a high-speed imaging system for whole-mouse peripheral nerve mapping at subcellular resolution, revealing detailed neural projections and patterns.

Cell · Jul 1, 2025Peer-reviewedNeuroscience

BigNeuron: A resource to benchmark and predict best-performing algorithms for automated reconstruction of neuronal morphology

Linus Manubens-Gil, Zhi Zhou, Hanbo Chen, Arvind Ramanathan, Xiaoxiao Liu, Yufeng Liu, Alessandro Bria, Todd A. Gillette, Zongcai Ruan, Jian Wu Yang, Miroslav Radojević, Ting Zhao, Li Cheng, Lei Qu, Siqi Liu, , Hanchuan Peng

BigNeuron benchmarks automatic neuron reconstruction algorithms using gold standard annotations and image quality metrics, showing that consensus methods outperform individual algorithms.

Nature Methods · Apr 17, 2023Peer-reviewedBioinformatics

The BRAIN Initiative Cell Census Data Ecosystem: A User's Guide

Michael Hawrylycz, Maryann Elizabeth Martone, Patrick R. Hof, Ed S. Lein, Aviv Regev, Giorgio A. Ascoli, Jan Gunnar Bjaalie, Hong‐Wei Dong, Satrajit Ghosh, Jesse A Gillis, Ronna P. Hertzano, David R. Haynor, Yongsoo Kim, Yufeng Liu, Jeremy A. Miller, , Brian Zingg

The paper provides a guide to the BRAIN Initiative Cell Census Network (BICCN) data ecosystem, its tools, and resources for analyzing brain cell types across species.

bioRxiv · Oct 26, 2022 · PreprintBioinformatics

Brain-wide single neuron reconstruction reveals morphological diversity in molecularly defined striatal, thalamic, cortical and claustral neuron types

Hanchuan Peng, Peng Xie, Lijuan Liu, Xiuli Kuang, Yimin Wang, Lei Qu, Hui Gong, Shengdian Jiang, Anan Li, Zongcai Ruan, Liya Ding, Chao Chen, Mengya Chen, Tanya L. Daigle, Zhangcan Ding, , Hongkui Zeng

Complete morphologies of 1,708 neurons, sparsely labelled and imaged whole-brain with fMOST, expose region-specific long-range projection rules and finer diversity than current transcriptomic subtypes capture.

bioRxiv · Sep 27, 2020 · PreprintNeuroscience