Author

Claudio Angione

Teesside UniversityORCID 0000-0002-3140-7909Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Claudio Angione1 paper

Biology Disciplines

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Systems Biology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:database / resource· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1

Frequent Co-Authors

Chaimaa TarziiD· 2 shared Dong‐Yup LeeiD· 2 shared Meiyappan LakshmananiD· 2 shared Alexandre OliveiraiD· 1 shared Alina RenziD· 1 shared Ana María Vega-LetteriD· 1 shared Anaís Sánchez‐CastilloiD· 1 shared Andreas DrägeriD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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2 shared papersSystems Biology

Chaimaa TarziORCID

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3 papers

Recent·Most cited

Sertraline and Carfilzomib Synergize to Target T-cell Malignancies with Serine/Glycine synthesis activity via Cholesterol Dysregulation, Cellular Stress and Immune Modulation

Paulien Verstraete, Elien Heylen, Anaís Sánchez‐Castillo, João Fontela, Lies Matthys, Sofie Meykens, Óscar Herranz, Suraj Verma, Le Minh Thao Doan, Linde Van Aerschot, Jelle Verbeeck, Jonathan Royaert, Michiel Vandenbosch, Ruben Jacobs, Gabriella Dow, , Kim De Keersmaecker

This paper shows that sertraline and carfilzomib work together to kill T-cell cancers by disrupting metabolism and changing the immune environment.

bioRxiv · Aug 19, 2026 · PreprintCancer Biology

A community-consensus reconstruction of Chinese Hamster metabolism enables structural systems biology analyses to decipher metabolic rewiring in lactate-free CHO cells

Pablo Di Giusto, Dong‐Hyuk Choi, Athanasios Antonakoudis, Vikash Gokul Duraikannan, Pierrick Craveur, Nicholas Luke Cowie, Tejaswini Ganapathy, Kannan Ramesh, Santiago Benavides-López, Camila A. Orellana, Natalia E. Jiménez, Leo Alexander Dworkin, James Morrissey, Igor Marín de Mas, Benjamin Strain, , Nathan E. Lewis

The paper presents iCHO3K, a comprehensive metabolic model of Chinese Hamster cells, and uses it to analyze metabolic changes in lactate-free cells, identifying structural insights into metabolic rewiring.

bioRxiv · Apr 10, 2025 · PreprintSystems Biology

FROG Analysis Ensures the Reproducibility of Genome Scale Metabolic Models

Karthik Raman, Miroslav Kratochvíl, Brett G. Olivier, Matthias König, Pratyay Sengupta, Dinesh Kumar Kuppa Baskaran, Tung V. N. Nguyen, Daniel Lobo, St. Elmo Wilken, Krishna Kumar Tiwari, Aswathy K. Raghu, Indumathi Palanikumar, Lavanya Raajaraam, Maziya Ibrahim, Sanjaay Balakrishnan, , Rahuman S. Malik‐Sheriff

The paper introduces FROG analysis to standardize reproducibility assessments of genome-scale metabolic models, resulting in full reproducibility of all tested models.

bioRxiv · Sep 24, 2024 · PreprintSystems Biology