Author

Kerstin Laurin

Lund UniversityORCID 0000-0002-3267-1111Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:cell-cell communication· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

Andreas BruzeliusiD· 2 shared Daniella Rylander OttossoniD· 2 shared Fredrik NilssoniD· 2 shared Janko KajteziD· 2 shared Malin ParmariD· 2 shared Mette HabekostiD· 2 shared Roger A. BarkeriD· 2 shared Alessandro FiorenzanoiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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2 shared papersBioengineering

Andreas BruzeliusORCID

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2 papers

Recent·Most cited

Transient matrix remodeling during direct cell-fate reprogramming enables self-assembly of dense neuronal niches

Kerstin Laurin, Mette Habekost, Fredrik Nilsson, Pinelopi Apostolaki, Emily B. Roloson, Jessica Giacomoni, Andreas Bruzelius, Milan Finn Wesseler, Roger A. Barker, Niels B. Larsen, Daniella Rylander Ottosson, David A. Weitz, Malin Parmar, Janko Kajtez

This paper describes a method to generate dense neuronal microcultures by combining fibroblast reprogramming with matrix remodeling in collagen microgels.

bioRxiv · Oct 28, 2026 · PreprintBioengineering

Injectable 3D microcultures enable intracerebral transplantation of mature neurons directly reprogrammed from patient fibroblasts

Janko Kajtez, Fredrik Nilsson, Kerstin Laurin, Andreas Bruzelius, Efraín Cepeda-Prado, Marcella Birtele, Roger A. Barker, Freja Herborg, Daniella Rylander Ottosson, Petter Storm, Alessandro Fiorenzano, Mette Habekost, Malin Parmar

This study develops a 3D microculture method to generate mature dopamine neurons from patient fibroblasts, which can be transplanted into a Parkinson's disease rat model to form functional neuron grafts.

Science Advances · Jun 6, 2025Peer-reviewedNeuroscience