Author

Thibaut Vignane

Leibniz Institute for Analytical Sciences - ISASORCID 0000-0002-3377-3187Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Research Focus:metabolism & bioenergetics· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Miloš R. FilipovićiD· 2 shared Abhishek AnandiD· 1 shared Andreas PapapetropoulosiD· 1 shared Andreas TrumppiD· 1 shared Andresa MessiasiD· 1 shared Anna Kieronska‐RudekiD· 1 shared Antonio Martı́nez-RuiziD· 1 shared Ashok Kumar JayaveluiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersBiochemistry

Miloš R. FilipovićORCID

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2 papers

Recent·Most cited

Sodium Aurothiomalate Induces Ferroptosis by Targeting GPX4 via Gold-Dependent Thiomalate Covalent Modification

Martín Hugo, Lissy Z. F. Gross, Andresa Messias, Lucía Alcober-Boquet, Thibaut Vignane, Biplab Ghosh, Nesrine Aroua, Lora Denson, Susana Delgado‐Martín, Kamini Kaushal, Umut Yildiz, Sebastian Müller, Antonio Martı́nez-Ruiz, Dario Ariel Estrin, Hellmut G. Augustin, , Hamed Alborzinia

This study shows sodium aurothiomalate induces ferroptosis by covalently modifying GPX4 through a gold-dependent mechanism, leading to tumor growth reduction in preclinical models.

bioRxiv · Nov 13, 2025 · PreprintBiochemistry

Endogenously produced hydrogen cyanide serves as a novel mammalian gasotransmitter

Karim Zuhra, Maria Petrosino, Lucia Janickova, Jovan Petrić, Kelly Ascenção, Thibaut Vignane, Moustafa M.R. Khalaf, Thilo Magnus Philipp, Stella Ravani, Abhishek Anand, Vanessa Martins, Sidnéia Sousa Santos, Serkan Erdemir, Sait Malkondu, Barbara Sitek, , Csaba Szabó

This study identifies endogenous hydrogen cyanide as a novel gasotransmitter in mammals, showing it regulates mitochondrial function and cell metabolism at optimal levels.

Nature Metabolism · Mar 3, 2025Peer-reviewedBiochemistry