José Fernández Navarro

Spatial and temporal transcriptomics reveal microglia-astroglia crosstalk in the amyloid-β plaque cell niche of Alzheimer’s disease

The paper uses spatial transcriptomics and in situ sequencing to study gene networks in the amyloid-β plaque niche of AD, revealing microglia-astroglia interactions and myelination abnormalities.

Molecular Atlas Of The Adult Mouse Brain

The paper creates a molecular atlas of the adult mouse brain using spatial transcriptomics, revealing new subregions and a molecular code for spatial annotation.

Spatial mapping of cell types by integration of transcriptomics data

The paper presents a probabilistic method integrating spatial transcriptomics and single-cell RNA-sequencing to spatially map cell types across tissues.

High-density spatial transcriptomics arrays for in situ tissue profiling

This paper introduces HDST, a high-resolution spatial transcriptomics method, and demonstrates its application in mouse brain tissue to resolve spatial expression patterns and cell types.

Charting Tissue Expression Anatomy by Spatial Transcriptome Decomposition

The paper introduces a probabilistic framework to analyze spatial transcriptomics data, identifying transcriptomic patterns corresponding to cell types and tissue components in mouse brain samples.