Martin C. Kahn

This study integrates multi-omic data from mouse and human choroid plexus to identify conserved molecular programs of epithelial function across species.

This study shows that a mutation in synaptobrevin 2 in mice leads to abnormal cortical activity patterns across sleep and wake states, resembling deep anaesthesia.

The paper investigates how micro-arousals affect neural activity in the motor cortex of sleep-deprived mice, finding increased slow wave activity immediately after micro-arousals.

This study shows that cholinergic signaling is crucial for GENUS-induced perivascular amyloid clearance in Alzheimer's mouse models.

Somnotate is a probabilistic classifier that improves sleep stage annotation in mice by identifying intermediate states and transitions, outperforming human experts.

The paper discusses findings on 40 Hz sensory stimulation's effects on the brain, supporting its potential benefits while noting technical limitations in amyloid burden studies.

This study introduces a new metric, oscillatory Quality (o-Quality), to quantify sleep spindle oscillatory strength in mice and links it to functional roles in sleep.

The paper identifies low amplitude neural activity segments during NREM sleep as OFF periods, showing they have distinct characteristics and new properties like vigilance-state-dependent duration.

This paper develops a closed-loop stimulation method using neuronal spiking activity to detect ON and OFF states during slow oscillations in freely moving mice.

This study shows that silencing specific cortical neurons in mice increases wakefulness and reduces sleep rebound after deprivation, highlighting the cortex's role in sleep regulation.

This study shows that hypothalamic stimulation increases cortical activity and accelerates sleep pressure buildup, indicating the hypothalamus regulates both state transitions and within-state arousal intensity.

This study shows that motor cortex modulates somatosensory processing through a cortico-thalamo-cortical pathway, with thalamic circuits playing a key role in tactile suppression.