Author

Justin Engelbert

Newcastle UniversityORCID 0000-0002-4255-9668Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 6 Organism:human· 6 Assay:scRNA-seq· 6 Approach:statistical model· 5 Research Focus:clustering· 4 Research Focus:database / resource· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2

Frequent Co-Authors

Muzlifah A. HaniffaiD· 6 shared Sarah Amalia TeichmanniD· 6 shared Emily StephensoniD· 5 shared Bayanne OlabiiD· 4 shared David HorsfalliD· 4 shared Elena PrigmoreiD· 4 shared Kerstin B. MeyeriD· 4 shared Laura JardineiD· 4 shared

Activity by Year

2021-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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6 shared papersDevelopmental Biology

Muzlifah A. HaniffaORCID

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6 papers

Recent·Most cited

An integrated single cell and spatial omics atlas of human prenatal development

Simone Webb, Antony Rose, Chuan Xu, Lloyd Steele, Masami A Kuri, Emily Stephenson, Kemal İnecik, Daniyal J. Jafree, April Rose Foster, Daniela Basurto-Lozada, Nana-Jane Chipampe, Anna Vathrakokoili Pournara, Marc‐Antoine Jacques, Ken To, Chloe Admane, , Muzlifah A. Haniffa

Human Developmental Cell Atlas integrates ~4.6 million cells/nuclei from 4-22 post-conception weeks into 454 refined cell types and maps 114 spatial niches across 6PCW whole-embryo sections.

bioRxiv · Apr 21, 2026 · PreprintDevelopmental Biology✦ In-depth digest

Single Cell Integration Characterises Metaplasia in Inflammatory Intestinal Diseases

Amanda J. Oliver, Ni Huang, Ruoyan Li, Raquel Bartolomé-Casado, Hogne Røed Nilsen, Victòria Gudiño, Elisa Melón-Ardanaz, Michael E. B. FitzPatrick, Nicholas M. Provine, Krzysztof Polański, Simon Koplev, Lisa Marie Milchsack, Emma Dann, Alexander V. Predeus, Batuhan Çakır, , Sarah Amalia Teichmann

The paper integrates single-cell RNA-seq datasets across the GI tract to identify epithelial metaplasia in inflammatory diseases, showing its role in inflammation through immune cell interactions.

bioRxiv · Oct 11, 2024 · PreprintGenomics

Cutaneous T cell lymphoma atlas reveals malignant Th2 cells supported by a B cell-rich microenvironment

Ruoyan Li, Johanna Strobl, Elizabeth F. M. Poyner, Fereshteh Torabi, Pasha Mazin, Nana-Jane Chipampe, Emily Stephenson, Louis C. S. Gardner, Bayanne Olabi, Rowen Coulthard, Rachel Anne Botting, Nina Zila, Elena Prigmore, Nusayhah Hudaa Gopee, Justin Engelbert, , Muzlifah A. Haniffa

The paper identifies Th2-like malignant cells in CTCL supported by a B cell-rich microenvironment through single-cell and spatial transcriptomics analysis.

bioRxiv · Nov 6, 2023 · PreprintGenomics

Multi-organ functions of yolk sac during human early development

Rachel A Botting, Issac Goh, Antony Rose, Simone Webb, Justin Engelbert, Yorick Gitton, Emily Stephenson, Mariana Quiroga Londoño, Michael Mather, Nicole Mende, Ivan Imaz-Rosshandler, Dave Horsfall, Daniela Basurto-Lozada, Nana-Jane Chipampe, Victoria Rook, , Muzlifah A. Haniffa

The paper maps the multi-organ functions of the human yolk sac during early development, revealing its roles in hematopoiesis, nutrition, and oxygen regulation.

bioRxiv · Aug 3, 2022 · PreprintDevelopmental Biology

Single cell mRNA signals reveal a distinct developmental state of KMT2A-rearranged infant B-cell acute lymphoblastic leukemia

Eleonora Khabirova, Laura Jardine, Tim H. H. Coorens, Simone Webb, Taryn D. Treger, Justin Engelbert, Tarryn Porter, Elena Prigmore, Grace Collord, Alice Piapi, Sarah Amalia Teichmann, Sarah Inglott, Owen Williams, Olaf T Heidenreich, Matthew D. Young, , Sam Behjati

The paper identifies a distinct developmental state in KMT2A-rearranged infant B-cell acute lymphoblastic leukemia using single-cell transcriptome analysis.

Nature Medicine · Mar 14, 2022Peer-reviewedGenomics

Intrinsic and extrinsic regulation of human fetal bone marrow haematopoiesis and perturbations in Down syndrome

Laura Jardine, Simone Webb, Issac Goh, Mariana Quiroga Londoño, Gary Reynolds, Michael William Mather, Bayanne Olabi, Emily Stephenson, Rachel Anne Botting, Dave Horsfall, Justin Engelbert, Daniel Maunder, Nicole Mende, Caitlin Murnane, Emma Dann, , Muzlifah A. Haniffa

This study uses single-cell RNA-sequencing to analyze fetal bone marrow development and identifies disruptions in hematopoiesis in Down syndrome.

Nature · Sep 29, 2021Peer-reviewedDevelopmental Biology