Leon Ullrich

B cell response to HCMV gH/UL116 elicits neutralizing and FcγR-activating antibodies

The paper identifies gH/UL116 as a target for antibodies that neutralize HCMV and activate FcγR, showing its potential as a vaccine candidate.

Identification of a pan-orthoebolavirus-reactive antibody from an rVSV-EBOV vaccinated individual

The paper identifies a broadly neutralizing antibody against multiple orthoebolaviruses from an rVSV-EBOV vaccinated individual and shows its protective efficacy in animal models.

Development of a multi-species luciferase-based double antigen ELISA for the detection of antibodies against Influenza A virus H5 clade 2.3.4.4b

This paper develops a multi-species luciferase-based double antigen ELISA for detecting H5 clade 2.3.4.4b-specific antibodies in various species, showing high sensitivity and specificity.

Next-generation all-in-one CRISPR/Cas9 multiply-edited CD30CAR-T cells:Potency despite risk of translocations

This study develops next-generation CD30CAR-T cells using CRISPR/Cas9 for multiplex editing, showing high potency but risks of translocations with combined knockouts.

Detection of low pre-existing humoral immunity against influenza virus H5N1 clade 2.3.4.4b in unexposed individuals

The paper assesses pre-existing humoral immunity against H5N1 clade 2.3.4.4b in unexposed individuals and finds low but distinct cross-neutralizing titers.