Clément M. Potel

This study reveals that phage T7 kinase broadly phosphorylates host and phage proteins, disabling bacterial defense systems through widespread phosphorylation.

This study uses multi-omics and biophysical phosphoproteomics to analyze BRAFV600E signaling, identifying ETV3 as a new downstream regulator and revealing mechanisms of drug resistance.

This paper introduces HT-PELSA, a high-throughput adaptation of a peptide-centric local stability assay, enabling sensitive protein-ligand profiling in diverse biological samples.

This study shows sublethal agrochemical exposure harms insect behavior, survival, and reproduction, with effects amplified by temperature changes, contributing to insect population decline.

The paper evaluates methods for inferring kinase-driven signaling pathways using phosphoproteomics data and kinase-substrate networks, finding that literature-curated networks with network propagation best recover ground truth interactions.

The paper identifies RNA-binding proteins involved in heterocyst differentiation in cyanobacteria using mass spectrometry and bioinformatics, revealing a new master regulator.

The paper identifies an ancient relaxant-inflammatory response in sponges during deflation, driven by actomyosin relaxation and associated with inflammation-like states.

The paper introduces a high-throughput glycoproteomics method to quantify brain glycoproteome changes induced by gut microbiome composition.

The paper assesses the impact of phosphorylation on protein thermal stability using phospho-TPP in HeLa cells, finding that phosphorylation affects stability less than previously reported.

The paper systematically maps the functional role of phosphorylation by analyzing phospho-deficient mutants in yeast and linking yeast phenotypes to human functional relevance.