Marc Vendrell

AKT-like kinase regulates early steps in the Trypanosoma brucei quorum sensing signalling pathway

This study identifies AKT-like kinase as a regulator of quorum sensing in Trypanosoma brucei, showing its role in differentiation and potential as a therapeutic target.

Fluorescence Characterization of Extracellular Vesicles using Single-Molecule Confocal Microscopy

This study develops a method to detect and quantify extracellular vesicles using fluorescent antibodies and single-molecule confocal microscopy, achieving femtomolar sensitivity without purification.

A brain atlas of synapse protein lifetime across the mouse lifespan.

The paper quantifies PSD95 protein lifetime in mouse synapses across lifespan and brain regions, revealing distinct patterns linked to development, behavior, and aging.

Genotype-phenotype map of an RNA-ligand complex

The paper systematically explores RNA-ligand interactions by analyzing mutations in an RNA aptamer, revealing complex phenotypic effects and training a model to predict RNA structure from epistasis.