Katherine I. Nagel

Neural dynamics for working memory and evidence integration during olfactory navigation in Drosophila

This study identifies a specific group of neurons in Drosophila that exhibit working memory and evidence integration during olfactory navigation, showing their role in maintaining goal-directed behavior after odor loss.

Ballistic food approaches in Parhyale hawaiensis require the antennae

This study shows that both first and second antennae in Parhyale hawaiensis are needed for effective food localization and stable swimming during foraging.

Molecular evolution of CO2-sensing ab1C neurons underlies divergent sensory responses in the Drosophila suzukii species group

The paper investigates how genetic changes in CO2-sensing neurons drive divergent oviposition preferences in Drosophila species.

CaBLAM! A high-contrast bioluminescent Ca2+ indicator derived from an engineered Oplophorus gracilirostris luciferase

This paper introduces CaBLAM, a bioluminescent Ca2+ indicator with improved dynamic range and Ca2+ affinity, enabling high-resolution imaging of cellular activity in cultured neurons and in vivo.

Disinhibition of a recurrent attractor gates a persistent goal signal for navigation

The paper investigates how disinhibition of a recurrent attractor network in flies enables rapid switching of persistent goal signals during navigation.

Central Complex representations of self-movement are sufficient to compute wind direction in flight

The paper shows that PFN representations of self-motion can decode wind direction during flight using computational models and neural networks.

Hierarchical Transformation of Navigational Variables into Coordinated Turning

This paper identifies a hierarchical steering circuit in Drosophila that transforms navigational signals into coordinated motor actions during walking and flight.

Inhibitory control of locomotor statistics in walking Drosophila

This study investigates how inhibitory neural circuits regulate locomotor statistics in Drosophila, identifying specific neurons that control search behavior and movement parameters.

Astrocyte growth during morphogenesis is driven by the Tre1/S1pr1 phospholipid-binding G protein-coupled receptor

The paper identifies Tre1 and S1pr1 as evolutionarily conserved regulators of astrocyte morphology through lipid signaling and competition for growth-promoting phospholipids.

The RNA-binding protein Imp specifies olfactory navigation circuitry and behavior in Drosophila

This study shows that the RNA-binding protein Imp, expressed in Type II neural stem cells, regulates olfactory navigation circuitry and behavior in Drosophila by specifying multiple circuit components and affecting neuronal morphology and function.

Scalable Apparatus to Measure Posture and Locomotion (SAMPL): a high-throughput solution to study unconstrained vertical behavior in small animals

The paper introduces SAMPL, a high-throughput system for measuring posture and locomotion in small animals, demonstrating its use in zebrafish and showing genetic and developmental effects on movement.

Active antennal movements in Drosophila tune wind encoding

This study investigates how active antennal movements in Drosophila influence wind encoding, showing that motor neurons control movement speed and that activation improves wind direction sensing.

A neural circuit for wind-guided olfactory navigation

The paper identifies a neural pathway in Drosophila that integrates odor and wind direction cues for upwind navigation.

Synaptic control of temporal processing in the Drosophila olfactory system

The paper investigates how short-term synaptic plasticity in Drosophila olfactory neurons affects temporal filtering of sensory stimuli and odor source localization.

Encoding and control of airflow orientation by a set of Drosophila fan-shaped body neurons

The paper identifies a group of Drosophila central complex neurons that encode airflow direction and are necessary for proper orientation to airflow.

Encoding of wind direction by central neurons in Drosophila

This study identifies how Drosophila central neurons decode wind direction by comparing signals from both antennae.

Elementary sensory-motor transformations underlying olfactory navigation in walking fruit-flies

This study identifies two elementary sensory-motor transformations in Drosophila olfactory navigation: an upwind run during odor and a search behavior at odor offset.

Dynamic integration of multisensory turn commands supports active reorienting during ongoing navigation.

The paper studies how Drosophila integrates multisensory cues during navigation, finding that conflicting cues are dynamically summed to produce intermediate turn commands.