Author

John Koren

University of FloridaORCID 0000-0002-6017-1763Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:differential expression· 2 Organism:mouse· 2 Assay:proteomics· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Organism:Drosophila· 1

Frequent Co-Authors

Jose Francisco AbisambraiD· 3 shared Marangelie Criado‐MarreroiD· 2 shared Nicholas T. SeyfriediD· 2 shared Sakthivel RaviiD· 2 shared Stefan ProkopiD· 2 shared Alexandria Ingram· 1 shared Anika M. S. HartziD· 1 shared Benoit I. GiassoniD· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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3 shared papersNeuroscience

Jose Francisco AbisambraORCID

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3 papers

Recent·Most cited

Progressive Supranuclear Palsy PERK haplotype B selectively translates DLX1 promoting tau toxicity

Christian B. Lessard, Diego Rubio-Rubio, Samantha G Tolton, Marangelie Criado‐Marrero, Sakthivel Ravi, Tristyn N. Garza, John Koren, Jennifer Phillips, Pritha Bagchi, Karen N. McFarland, Deepak Chhangani, Todd Eliot Golde, Benoit I. Giasson, Jada M. Lewis, Paramita Chakrabarty, , Jose Francisco Abisambra

This study identifies a PERK-B/DLX1 pathway as a novel driver of tau pathology in human PSP and flies, showing DLX1 promotes tau toxicity.

bioRxiv · Jun 30, 2025 · PreprintNeuroscience

Repetitive mild traumatic brain injury impairs resting state fMRI connectivity and alters protein profile signaling networks

Sakthivel Ravi, Marangelie Criado‐Marrero, Daylin Barroso, Isadora Braga, MacKenzie L. Bolen, Uriel Rubinovich, Gabriela P. Hery, Matteo M. Grudny, John Koren, Stefan Prokop, Marcelo Febo, Jose Francisco Abisambra

This study investigates how repetitive mild traumatic brain injury (rmTBI) affects brain functional connectivity and protein profiles in mice, revealing altered connectivity and inflammatory responses.

bioRxiv · Sep 21, 2022 · PreprintNeuroscience

Broad kinase inhibition mitigates early neuronal dysfunction and cognitive deficits in tauopathy

Shon A. Koren, Matthew J. Hamm, Ryan Cloyd, Sarah N. Fontaine, Emad A. Chishti, Chiara Lanzillotta, Jennifer Rodriguez-Rivera, Alexandria Ingram, Michelle C. Bell, Sara María Galvis Escobar, Nicholas Zulia, Fabio Di Domenico, Duc Duong, Nicholas T. Seyfried, David K. Powell, , Jose Francisco Abisambra

The paper treats early-stage tau transgenic mice with a multi-target kinase inhibitor, showing cognitive improvement and proteomic shifts similar to Alzheimer's disease in humans.

bioRxiv · Jul 31, 2020 · PreprintNeuroscience