Author

Jamshid Abdul-Ghafar

6Department of Pathology, Molecular and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, New York, New York.ORCID 0000-0002-6575-8870Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:human· 2 Assay:scRNA-seq· 2 Research Focus:cell-cell communication· 1 Approach:deep learning· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

Robert P. SebraiD· 2 shared Aditi Prasad· 1 shared Alan SotoiD· 1 shared Alexander A. MikryukoviD· 1 shared Alexander M. TsankoviD· 1 shared Amine MazineiD· 1 shared Amir HorowitziD· 1 shared Andrea WolfiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersCell Biology

Robert P. SebraORCID

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Author profile →

2 papers

Recent·Most cited

Dysregulated TGFb-ERK Signaling Drives Aberrant Extracellular Matrix Production in Noonan Syndrome-Associated Pulmonary Valve Stenosis

Clifford Z. Liu, Shrey D. Patel, Simone Sidoli, Aditi Prasad, Daniel Charytonowicz, Amine Mazine, Alexander A. Mikryukov, Jamshid Abdul-Ghafar, Elizabeth S. Kahn, Dejauwne L. Young, George Arthur Porter Jr., Philip J. Katzman, Stephen Pruett Sanders, Chrystalle Katte Carreon, Dirk Hubmacher, , Bruce D. Gelb

This study identifies dysregulated TGFβ-ERK signaling as a driver of aberrant extracellular matrix production in Noonan syndrome-associated pulmonary valve stenosis using iPSC models and patient tissue.

bioRxiv · Jan 20, 2026 · PreprintCell Biology

Single cell view of tumor microenvironment gradients in pleural mesothelioma

Bruno Giotti, Komal Dolasia, William Zhao, Peiwen Cai, Robert Sweeney, Elliot Merritt, Evgeny Kiner, Grace S. Kim, Atharva Bhagwat, Thinh Nguyen, Samarth Hegde, Bailey G. Fitzgerald, Sanjana Shroff, Travis Dawson, Monica Garcia-Barros, , Alexander M. Tsankov

This paper uses single-cell RNA-sequencing to analyze the tumor microenvironment in pleural mesothelioma, identifying gene programs, fetal-like endothelial cells, and a new therapeutic target.

bioRxiv · Mar 14, 2024Cancer Biology