Juliette Fédry

In-cell structural insights into fungal ER stress responses

This study uses structural biology techniques to show that ER stress in yeast increases inactive ribosomes and modulates elongation factors, suggesting modest translation inhibition as a stress response.

Substrate-directed control of N-glycosylation in the endoplasmic reticulum calibrates signal reception at the cell-surface

The paper identifies an ER pathway that regulates N-glycosylation by modulating OST-A activity, impacting cell-surface signaling and tissue development.

NAC-mediated ribosome localization regulates cell fate and metabolism in intestinal stem cells

Hybrid sequence-structure based HMM models leverage theidentification of homologous proteins: the example of class II fusion

The paper introduces a hybrid sequence-structure HMM method to identify homologous proteins with low sequence identity and structural conservation, demonstrating its effectiveness in detecting class II fusion proteins.