Author

Jason C. Andrechak

University of PennsylvaniaORCID 0000-0002-6659-9488Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 1 Genomics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1 Organism:non-human primate· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Dennis E. DischeriD· 3 shared Lawrence J. DoolingiD· 3 shared Jerome IriantoiD· 2 shared A. Jalil· 1 shared Alex Kasznel· 1 shared Alişya A. AnlaşiD· 1 shared Charlotte R. PfeiferiD· 1 shared Cory M. AlveyiD· 1 shared

Activity by Year

2018-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersBioengineering

Dennis E. DischerORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Clustered macrophages cooperate to eliminate tumors via coordinated intrudopodia

Lawrence J. Dooling, Alişya A. Anlaş, Michael P. Tobin, Nicholas M. Ontko, Tristan Marchena, Maximilian Wang, Jason C. Andrechak, Dennis E. Discher

This study shows that macrophage clusters enhance tumor phagocytosis through coordinated intrudopodia extending between cancer cells.

Proceedings of the National Academy of Sciences · Jul 1, 2025Peer-reviewedBioengineering

Heterogeneous strains in tissue collagen show that high strains locally suppress degradation by collagenase

Karanvir Saini, M. Tiwari, Sangkyun Cho, A. Jalil, Manasvita Vashisth, Jerome Irianto, Jason C. Andrechak, Lawrence J. Dooling, Cory M. Alvey, Alex Kasznel, David M. Chenoweth, K. Yamamoto, Dennis E. Discher

This paper investigates how mechanical strain affects collagen degradation in tendon and heart tissues, finding that moderate strains suppress degradation while higher strains do not.

bioRxiv · Feb 7, 2021 · PreprintMolecular Biology

Live cell monitoring for factors affecting genome variation

Yuntao Xia, Kuangzheng Zhu, Jerome Irianto, Jason C. Andrechak, Lawrence J. Dooling, Charlotte R. Pfeifer, Dennis E. Discher

The paper monitors live cell fluorescence to quantify aneuploidy-inducing perturbations in lung cancer and iPS cells, revealing increased chromosome mis-segregation and rare fluorescent-null cells.

bioRxiv · Dec 31, 2018 · PreprintGenomics