Margaret A. Scull

This study shows that H5N1 viruses from B3.13 and D1.1 lineages have reduced infectivity in human respiratory cultures due to impaired neuraminidase and polymerase activities, suggesting lower pandemic risk than traditional models indicate.

The paper introduces an inverse Transwell assay to study mucus barrier function against respiratory viruses and identifies MUC5AC's role in antiviral defense.

This study identifies infection-specific long-chain fatty acid metabolism as a broad anti-enterovirus target by showing that polyunsaturated LCFAs inhibit multiple steps of the virus life cycle.

The paper characterizes gene regulatory networks in human airway epithelial cells and identifies cell type-specific responses to type I interferon.

This study evaluates AAV6-mediated MUC5AC siRNA delivery to reduce mucin overexpression and improve mucociliary clearance in asthma models.

This study shows that female sex hormones enhance gonococcal colonization at the endocervix by altering mucus production and structure, increasing bacterial microcolony size and number.