Josef D. Järhult

Polymicrobial catheter biofilms sustain susceptible Enterococcus faecalis and Escherichia coli during β-lactam treatment

The paper shows that susceptible Enterococcus faecalis and Escherichia coli in catheter biofilms survive β-lactam treatment through mutualistic interactions and persister-like states, without resistance.

Heterogeneity and Metabolic Diversity among Enterococcus Species during Long-term Colonization

This study identifies genetic and metabolic diversity among Enterococcus species in ICU patients, revealing multiple clones, horizontal gene transfer, and challenges in species identification.

Identification of unique and potent inhibitors of SARS-CoV-2 main protease from DNA-encoded chemical libraries

This paper identifies potent SARS-CoV-2 main protease inhibitors from a DNA-encoded chemical library using affinity-based selection, achieving an IC50 of 30 nM for compound SLL11.

Loss of Y in leukocytes as a risk factor for critical COVID-19 in men

The paper investigates LOY in leukocytes as a risk factor for severe COVID-19 in men, finding higher LOY levels in critical cases and associations with immune-related outcomes.

A high-quality Genome and Comparison of Short versus Long Read Transcriptome of the Palaearctic duck Aythya fuligula (Tufted Duck)

The paper presents a high-quality genome and transcriptome of the tufted duck, comparing short and long-read sequencing technologies for transcriptome assembly.