The paper investigates retrograde suppression of post-tetanic potentiation at the mossy fiber-CA3 synapse using acute mouse hippocampal slices, finding Ca2+-dependent regulation.

eNeuro · Feb 16, 2021Peer-reviewedNeuroscience

ShuTu: Open-Source Software for Efficient and Accurate Reconstruction of Dendritic Morphology

Dezhe Z. Jin, Ting Zhao, David L. Hunt, Rachel P. Tillage, Ching-Lung Hsu, Nelson Spruston

ShuTu is a software tool that enables efficient and accurate reconstruction of dendritic morphology from bright-field microscopy images through automated identification and manual correction.

Frontiers in Neuroinformatics · Oct 31, 2019Peer-reviewedNeuroscience

The Transcriptional Logic of Mammalian Neuronal Diversity

Ken Sugino, Erin Clark, Anton Schulmann, Yasuyuki Shima, Lihua Wang, David L. Hunt, Bryan M. Hooks, Dimitri Tränkner, Jayaram V. Chandrashekar, Serge Picard, Andrew L. Lemire, Nelson Spruston, Adam W. Hantman, Sacha B. Nelson

The paper identifies homeobox transcription factors as key drivers of neuronal diversity through improved expression metrics and links long genes to regulatory elements and mobile elements.

bioRxiv · Oct 24, 2017 · PreprintEvolutionary Biology