Author

Juan Hong

University of Nebraska Medical CenterORCID 0000-0002-7894-8403Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Assay:imaging· 1 Research Focus:metabolism & bioenergetics· 1 Organism:mouse· 1 Organism:rat· 1

Frequent Co-Authors

Abhinav DiwaniD· 1 shared Andrew W. NorrisiD· 1 shared Antentor Othrell Hinton Jr.iD· 1 shared Ashutosh KumariD· 1 shared Chad Eric GrueteriD· 1 shared David R. RawnsleyiD· 1 shared Dong WangiD· 1 shared E. Dale AbeliD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperCell Biology

Abhinav DiwanORCID

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2 papers

Recent·Most cited

Neural Inflammation in Thoracic Dorsal Root Ganglia Mediates Cardiopulmonary Spinal Afferent Sensitization in Chronic Heart Failure

Juan Hong, Samuel Gillman, Peter Ricci Pellegrino, Gang Zhao, Rongguo Ren, Steven J. Lisco, Irving H. Zucker, Dong Wang, Hanjun Wang

This study identifies neuroinflammation in thoracic dorsal root ganglia as a driver of cardiopulmonary afferent sensitization in chronic heart failure, showing that anti-inflammatory strategies can reduce inflammation and improve cardiac outcomes.

bioRxiv · Oct 22, 2025 · PreprintNeuroscience

Lysosomal LRRC8 complex regulates lysosomal pH, morphology and systemic glucose metabolism

Ashutosh Kumar, Yonghui Zhao, Litao Xie, Rahul Chadda, John D. Tranter, Ryan T. Mikami, Nihil Abraham, Juan Hong, Ethan Yang Feng, David R. Rawnsley, Haiyan Liu, Kayla M. Henry, Gretchen A. Meyer, Meiqin Hu, Haoxing Xu, , Rajan Sah

This study shows that the lysosomal LRRC8 complex regulates lysosomal pH, morphology, and systemic glucose metabolism by affecting mTOR signaling and autophagic flux.

Science Advances · Sep 26, 2025Peer-reviewedCell Biology