G. Campbell Teskey

Connexin 40 deficiency alters the temporal profile of postictal oxygen dynamics following focal seizures.

This study shows that Cx40 deficiency changes the timing of oxygen recovery after seizures without affecting seizure duration.

Contralesional hippocampal spreading depolarization promotes functional recovery after stroke

This study shows that contralesional hippocampal spreading depolarization improves functional recovery after hippocampal stroke in mice.

A Markovian neural barcode representing mesoscale cortical spatiotemporal dynamics.

The paper introduces a Markovian neural barcode to represent mesoscale cortical dynamics using a Continuous Time Markov Chain model derived from semi-binary non-negative matrix factorization.

Sudden unexpected death in epilepsy is prevented by blocking postictal hypoxia

This study shows that blocking postictal hypoxia prevents SUDEP in mice by preventing seizure-induced vasoconstriction.

New neurons in old brains: A cautionary tale for the analysis of neurogenesis in post-mortem tissue.

This study shows that delayed tissue fixation in post-mortem rats reduces observed neurogenesis, suggesting fixation methods may explain apparent differences in human versus rodent neurogenesis.

In vivo assessment of mechanisms underlying the neurovascular basis of postictal amnesia

This study investigates the role of postictal hypoperfusion/hypoxia in memory impairments after seizures, finding that synaptic plasticity is specifically affected while other network functions remain intact.

Seizures cause sustained microvascular constriction associated with astrocytic and vascular smooth muscle Ca2+ recruitment

The paper shows seizures cause prolonged microvascular constriction in mice, linked to astrocytic and vascular smooth muscle Ca2+ changes, and COX-2 dependency.

Postsynaptic Pannexin-1 Facilitates Anandamide Uptake to Modulate Glutamate Release and Enhance Network Excitability

This study shows that postsynaptic pannexin-1 regulates glutamate release and network excitability by facilitating anandamide clearance and modulating TRPV1 activity.