Author

Madeleine C. Mankowski

National Institutes of HealthORCID 0000-0002-8640-174XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Benhur LeeiD· 1 shared Brett D. LindenbachiD· 1 shared Cameron O. SchmitziD· 1 shared Craig B. WileniD· 1 shared Danica F. BesavillaiD· 1 shared David van DijkiD· 1 shared Davide AngelettiiD· 1 shared Fernando de Miguel· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperGenetics

Benhur LeeORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Antibodies, Memory B Cells, and Antigen Valency Reshape B Cell Responses to Drifted Influenza Virus Vaccination

Laura Reusch, Nimitha R. Mathew, Karin Schön, Ivan Košík, James S. Gibbs, Madeleine C. Mankowski, Danica F. Besavilla, Jonathan Wilson Yewdell, Mats Bemark, Davide Angeletti

This study investigates how vaccine antigen valency and pre-existing memory B cells influence B cell responses to drifted influenza virus, showing differential effects on germinal center dynamics and immunodominance.

bioRxiv · Nov 7, 2025 · PreprintImmunology

Genome-wide CRISPR screen reveals host genes that regulate SARS-CoV-2 infection

Jin Wei, Mia Madel Alfajaro, Ruth E. Hanna, Peter C. DeWeirdt, Madison S. Strine, William J. Lu-Culligan, Shang‐Min Zhang, Vincent R. Graziano, Cameron O. Schmitz, Jennifer Chen, Madeleine C. Mankowski, Renata B. Filler, Victor Gasque, Fernando de Miguel, Huacui Chen, , Craig B. Wilen

A genome-wide CRISPR screen with SARS-CoV-2 recovers ACE2 and Cathepsin L and nominates SWI/SNF, TGF-beta signalling and HMGB1 as pro-viral; pathway inhibitors blocked virus-induced death.

bioRxiv · Jun 16, 2020 · PreprintGenetics