Marina Mione

Telomerase and Alternative Lengthening of Telomeres coexist in the regenerating zebrafish caudal fins

This study shows that telomere length is maintained in telomerase-deficient zebrafish during caudal fin regeneration via the ALT pathway, suggesting its role in supporting high cell proliferation rates.

Cell Marker Accordion: interpretable single-cell and spatial omics annotation in health and disease

The paper introduces Cell Marker Accordion, a tool for accurate and interpretable single-cell and spatial omics annotation across health and disease contexts.

Telomeric antisense oligonucleotides reduce premature aging phenotypes in telomerase mutant zebrafish

This study shows that telomeric antisense oligonucleotides reduce premature aging in telomerase mutant zebrafish by inhibiting DDR signaling.

A TranSNP in the DDIT4 mRNA can impact its translation efficiency and modulate p53-dependent responses in cancer cells

The paper identifies a tranSNP in DDIT4 mRNA that affects translation efficiency and modulates p53-dependent responses in cancer cells.

Disease modeling by efficient genome editing using a near PAM-less base editor in vivo.

This paper introduces a near PAM-less base editor that enables efficient point mutation introduction in zebrafish for disease modeling.

Precise base editing for the in vivo study of developmental signaling and human pathologies in zebrafish

The paper demonstrates the use of base editors to generate precise point mutations in zebrafish for studying developmental signaling and human pathologies.