Siglec-F Protects Against Elastase-induced Lung Inflammation and Emphysema in Mice
Qihua Ye, Naoko Hara, Yan Hu, Marika Orlov, Bradford J. Smith, Tonya M. Brunetti, Rachel Z. Blumhagen, Zhenghui Liu, Bifeng Gao, Mélanie Königshoff, William J. Janssen, Christopher M. Evans
This study shows that Siglec-F protects against elastase-induced lung inflammation and emphysema by regulating airspace macrophages in mice.
bioRxiv · Sep 16, 2025 · PreprintImmunology