Author

Carlos Flores

University of BaselORCID 0000-0002-9178-6939Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 2 Organism:bacteria (other)· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Research Focus:drug response / drug discovery· 1 Organism:E. coli· 1

Frequent Co-Authors

Christoph DehioiD· 3 shared Urs JenaliD· 3 shared Sarah Tschudin‐SutteriD· 2 shared Steffi Klimke· 2 shared Adrian EgliiD· 1 shared Amanzhol KurmasheviD· 1 shared Andrea RockeriD· 1 shared Andreas KaczmarczykiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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Curved chords = mutual co-authorship

3 shared papersMicrobiology

Christoph DehioORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Competition against the intestinal microbiota selects for pathoadaptive traits in ESBL E. coli

Pramod Kumar Jangir, Leonardo F. Lemos Rocha, Marco Molari, Nicolas Wenner, Cecilia Fruet, Pablo Manfredi, Carlos Flores, Anna Sintsova, Roxanne Mouchet, Lisa Diner, Anouk Bertola, Svenja Förster, Elisa Lee, MiCayla Johnson, Malenka Kunz, , Médéric Diard

This study identifies how the intestinal microbiota drives the evolution of pathoadaptive traits in ESBL E. coli through adhesion and biofilm formation.

bioRxiv · Jun 29, 2026 · PreprintMicrobiology

Monitoring intracellular antibiotic concentrations in real-time using allosteric biosensors

Daria D. Fleckenstein, Andreas Kaczmarczyk, Niklas Breitenbach-Netter, Gili Rosenberg, Roman Peter Jakob, Isabel Sorg, Amanzhol Kurmashev, Carlos Flores, Eva Jiménez‐Siebert, Elinor Morris, Steffi Klimke, Sarah Tschudin‐Sutter, Andreas R. Hierlemann, Timm Maier, Christoph Dehio, , Knut Drescher

The paper develops genetically-encoded biosensors to monitor antibiotic concentrations inside bacterial cells and tissues in real-time, revealing antibiotic exposure dynamics and penetration in infection models.

bioRxiv · Feb 5, 2026 · PreprintMicrobiology

Genome-scale CRISPRi profiling reveals metabolic vulnerabilities of uropathogenic Escherichia coli in human urine

Monica Ortelli, Rūta Prakapaitė, Antonia Müller, Solange Miele, Cinzia Fino, Steffi Klimke, Sarah Tschudin‐Sutter, Urs Jenal, Carlos Flores, David Bikard, Christoph Dehio

This study uses CRISPRi to identify metabolic vulnerabilities of UPEC in urine, highlighting ALS II as a druggable target.

bioRxiv · Oct 31, 2025 · PreprintMicrobiology