Author

Wouter P. F. Driever

Leiden UniversityORCID 0000-0002-9250-0381Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Mario van der SteltiD· 3 shared A.C. Harms· 1 shared A.M.R. van den Bosch· 1 shared Albert J. R. HeckiD· 1 shared Annemieke J.M. RozemülleriD· 1 shared Anto PavloviciD· 1 shared Bart EvertsiD· 1 shared Berend GagesteiniD· 1 shared

Activity by Year

2022-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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Curved chords = mutual co-authorship

3 shared papersNeuroscience

Mario van der SteltORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Synthesis of Cyclopropene-Modified Fatty Acids Allows Single Cell Quantification of Uptake By Immune Cells

Luuk Reinalda, Graham A. Heieis, Laura Bogue Edgerton, Kristine Bertheussen, Diana Torres‐García, Marouane el Boujadayni, Kas Steuten, Jeroen M. Punt, Wouter P. F. Driever, Connor Corrigan, Xinyuan Wang, Bart Everts, David K. Finlay, Mario van der Stelt, Sander I. van Kasteren

This study develops clickable fatty acids to quantify single-cell uptake by immune cells, finding polyunsaturated fatty acids are preferentially taken up by various immune cell types.

Angewandte Chemie International Edition · May 28, 2026Peer-reviewedBiochemistry

Foamy microglia link oxylipins to disease progression in multiple sclerosis

D. van der Vliet, X. Di, Tatiana M. Shamorkina, Claire Coulon-Bainier, Anto Pavlovic, I.A.C.M. van der Vliet, Y. Zeng, Will Macnair, Noëlle van Egmond, J.Q.A. Chen, A.M.R. van den Bosch, Hendrik J. Engelenburg, Dennis D. Wever, M.R.J. Mason, Wouter P. F. Driever, , Mario van der Stelt

The paper identifies foamy microglia as contributors to disease progression in secondary progressive MS, linking oxylipins to lesion expansion and proposing monoacylglycerol lipase as a therapeutic target.

Leiden Repository (Leiden University) · Jan 1, 2026Peer-reviewedNeuroscience

Disruption of Tonic Endocannabinoid Signaling Triggers the Generation of a Stress Response

Gavin N. Petrie, Georgia Balsevich, Tamás Füzesi, Robert J. Aukema, Wouter P. F. Driever, Mario van der Stelt, Jaideep S. Bainsand, Matthew N. Hill

The paper shows that disrupting tonic endocannabinoid signaling increases HPA axis activation by enhancing CRH neuron activity in the PVN, leading to stress-like behaviors and elevated corticosterone.

bioRxiv · Sep 27, 2022 · PreprintNeuroscience