Robbert J. Rottier

Vessel Organoids Reveal FOXF1 Variant-Specific Regulation of Mesoderm and Capillary Development

The paper uses vessel organoids to study how different FOXF1 variants affect mesoderm and capillary development in humans, showing variant-specific disruptions and potential therapeutic rescue.

Deciphering Endothelial and Mesenchymal Organ Specification in Vascularized Lung and Intestinal Organoids

This study develops a human pluripotent stem cell-derived organoid system to investigate vascular, mesenchymal, and epithelial co-development in lung and intestinal organoids, revealing organ-specific endothelial and mesenchymal features.

Distinct roles for SOX2 and SOX21 in differentiation, distribution and maturation of pulmonary neuroendocrine cells

This study investigates the roles of SOX2 and SOX21 in the differentiation, distribution, and maturation of pulmonary neuroendocrine cells, showing that SOX2 suppresses precursor cell differentiation while SOX21 promotes it.

CLASP1 is essential for neonatal lung function and survival in mice

This study shows that CLASP1 is critical for neonatal lung function and survival in mice by regulating microtubule dynamics and lung development.