Thomas Bock

This study identifies PAIP1 as a cofactor for mRNA export and shows it couples nuclear to cytoplasmic mRNP remodeling and poly(A) homeostasis, affecting mRNA stability and development.

This study shows that laminin-α2 is essential for maintaining the myotendinous junction structure, and mechanical unloading affects its integrity in a mouse model of LAMA2-related muscular dystrophy.

The paper identifies new interactors of eIF3f in human muscle cells using BioID technology, revealing both nuclear and cytoplasmic interactions relevant to muscle structure and function.

The paper maps Staphylococcus aureus microgeography in human tissue using AI-guided imaging and finds antibiotic failure is linked to intracellular bacterial persistence and metabolic constraints.

The paper shows that epistatic interactions between RpoB and GyrA mutations in Mycobacterium tuberculosis can lead to high-fitness double-resistant strains, which are prevalent in clinical isolates.

This study identifies Safb1 as a regulator of neuron production in adult hippocampal neural stem cells by enhancing Drosha-mediated cleavage of NFIB mRNA, preventing glial differentiation.