Author

Mehdi Khaled

InsermORCID 0000-0002-9880-858XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Organism:human· 2 Assay:proteomics· 2 Approach:statistical model· 2 Research Focus:cancer & tumor microenvironment· 1 Assay:ChIP-seq· 1

Frequent Co-Authors

Alexandrine CarminatiiD· 1 shared Aline MatheyiD· 1 shared Andrey S. KlymchenkoiD· 1 shared Asaf ZviraniD· 1 shared Carmit LevyiD· 1 shared Christophe A. J. GirardiD· 1 shared Danna SheinboimiD· 1 shared Emna OuniiD· 1 shared

Activity by Year

2017-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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1 shared paperCancer Biology

Alexandrine CarminatiORCID

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Author profile →

3 papers

Recent·Most cited

Endosomal membrane state governs trafficking and cell migration under TFEB control

Julie Patat, Aline Mathey, Emna Ouni, Pallavi Mathur, Hugo Lachuer, Nadia Elkhatib, Mehdi Khaled, Gaël Blivet-Bailly, Andrey S. Klymchenko, Julio Lopes Sampaio, Kristine Schauer

This study shows TFEB regulates endosomal membrane fluidity and cargo trafficking, affecting cell migration and adhesion in bladder cancer.

bioRxiv · Sep 8, 2026 · PreprintCell Biology

USP9X is a mechanosensitive deubiquitinase that controls tumor cell invasiveness and drug response through YAP stabilization

Pierric Biber, Alexandrine Carminati, Walaa Mohager, Mickaël Ohanna, Christophe A. J. Girard, Margaux Lecacheur, Mira Kahil, Océane Bouvet, Marie Irondelle, Stéphane Audebert, Mehdi Khaled, Sophie Tartare‐Deckert, Marcel Deckert

This study identifies USP9X as a mechanosensitive deubiquitinase that stabilizes YAP to enhance tumor cell invasiveness and drug resistance.

Cell Reports · Oct 1, 2025Peer-reviewedCancer Biology

OCT4 Impedes Cell Fate Redirection By The Melanocyte Lineage Master Regulator MITF

Danna Sheinboim, Itay Maza, Iris Dror, Shivang Parikh, Vladislav Krupalnik, Rachel E. Bell, Asaf Zviran, Yusuke Suita, Ofir Hakim, Yael Mandel‐Gutfreund, Mehdi Khaled, Jacob H. Hanna, Carmit Levy

The paper shows OCT4 prevents cell fate change by blocking MITF's effects in embryonic stem cells and other differentiated cells.

Nature Communications · Oct 12, 2017Peer-reviewedDevelopmental Biology