Jonghwan Kim

DNA methylation maintenance by DNMT1 is essential for human trophoblast stem cell homeostasis and differentiation

This study shows that DNMT1 is crucial for human trophoblast stem cell proliferation, differentiation, and DNA methylation, linking its dysfunction to recurrent pregnancy loss.

Identifying membrane-bound transcriptional regulatory proteins from rare but evolutionarily conserved domain combinations

The paper identifies novel membrane-bound transcriptional regulators by analyzing rare, evolutionarily conserved domain combinations in membrane proteins.

Mechanical Rejuvenation of Mesenchymal Stem Cells from Aged Patients

This study shows that mechanical conditioning improves the regenerative potential of aged mesenchymal stem cells by reducing senescence and altering their genetic landscape.

Histone demethylome map reveals combinatorial gene regulatory functions in embryonic stem cells

The paper identifies combinatorial functions of histone demethylases in gene regulation of mouse embryonic stem cells by analyzing their genome-wide binding patterns.

Systematic discovery of endogenous human ribonucleoprotein complexes

The paper systematically identifies endogenous human ribonucleoprotein complexes using a proteomics method and provides a resource for studying RNA-associated protein complexes.