Author

David B. Thompson

Harvard UniversityORCID 0000-0003-2009-4975Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:drug response / drug discovery· 1 Research Focus:perturbation response prediction· 1

Frequent Co-Authors

Cory J. SmithiD· 1 shared Denitsa MilanovaiD· 1 shared George McDonald ChurchiD· 1 shared Hannu MyllykallioiD· 1 shared Ira MellmaniD· 1 shared Khaled Said· 1 shared Marc GüelliD· 1 shared Matthew Dysart· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperSynthetic Biology

Cory J. SmithORCID

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2 papers

Recent·Most cited

ImmunologybioRxivPreprintJun 3, 2026

From prediction to engagement: defining tumor-reactive T cells through biological interaction

Nicholas P. Restifo, Suman Kumar Vodnala, David B. Thompson…·Denitsa Milanova

The paper identifies tumor-reactive T cells by focusing on productive T-cell engagement with tumor cells, showing that such interactions enrich for neoantigen-reactive clonotypes with progenitor-like states.

DOI 10.64898/2026.05.31.729129

humanbulk RNA-seq

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Synthetic BiologybioRxivPreprintFeb 3, 2020

CRISPR-mediated biocontainment

Oscar Castanon, Cory J. Smith, Parastoo Khoshakhlagh…·George McDonald Church

The paper develops CRISPR-based biocontainment circuits using transposable elements to induce cell death and create kill-switches for controlling cell lines.

6 citations

humanexperimental assay

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