Author

Georg Dechant

Innsbruck Medical UniversityORCID 0000-0003-2011-9415Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2 Neuroscience· 1

Signature Assays, Organisms & Methods

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Assay:ChIP-seq· 3 Research Focus:differential expression· 3 Research Focus:gene regulatory network inference· 2 Assay:Hi-C· 2 Organism:mouse· 2 Research Focus:spatial domain detection· 2 Approach:statistical model· 2 Approach:experimental assay· 1

Frequent Co-Authors

Galina ApostolovaiD· 3 shared Aleksandra A. KolodziejczykiD· 1 shared Alexander KukaleviD· 1 shared Alphonse ChuiD· 1 shared Altuna AkaliniD· 1 shared Amelie Nagel· 1 shared Ana PomboiD· 1 shared Andrea M. ChiarielloiD· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersMolecular Biology

Galina ApostolovaORCID

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3 papers

Recent·Most cited

SATB2 organizes the 3D genome architecture of cognition in cortical neurons

Nico Wahl, Sergio Espeso‐Gil, Paola Chietera, Amelie Nagel, Aodán Laighneach, Derek W. Morris, Prashanth Rajarajan, Schahram Akbarian, Georg Dechant, Galina Apostolova

The paper shows SATB2 influences 3D genome structure in cortical neurons, affecting gene expression and cognitive-related functions.

Molecular Cell · Jan 21, 2024Peer-reviewedNeuroscience

Chromatin reorganization during myoblast differentiation involves the caspase-dependent removal of SATB2

Ryan A. V. Bell, Mohammad H Al-Khalaf, Steve Brunette, Dalal Alsowaida, Alphonse Chu, Hina Bandukwala, Georg Dechant, Galina Apostolova, Francis Jeffrey Dilworth, Lynn A. Megeney

This study shows that SATB2 removal, mediated by caspase 7 cleavage, is critical for chromatin reorganization during myoblast differentiation.

Cells · Mar 11, 2022Peer-reviewedMolecular Biology

Cell-type specialization in the brain is encoded by specific long-range chromatin topologies

Warren Winick‐Ng, Alexander Kukalev, Izabela Harabula, Luna Zea Redondo, Dominik Szabó, Mandy Meijer, Leonid Serebreni, Yingnan Zhang, Simona Bianco, Andrea M. Chiariello, Ibai Irastorza-Azcárate, Luca Fiorillo, Francesco Musella, Christoph J. Thieme, Ehsan Irani, , Ana Pombo

The paper investigates cell-type specific 3D chromatin structures in the brain using immunoGAM, finding TAD melting, neuron-specific contacts, and compartmentalization patterns related to gene expression and neurodegenerative diseases.

bioRxiv · Apr 2, 2020 · PreprintMolecular Biology