Gabriele Sales

This study shows CD300e deficiency worsens obesity-related metabolic dysfunction in mice and human cells, highlighting its role in adipose tissue macrophage metabolism and potential as a therapeutic target.

This study compares the heatwave resilience of native and non-indigenous Sporobolus species in salt marshes, finding the non-indigenous species more resilient.

The paper introduces an AI-driven pipeline using Protein Language Models to discover hidden CLE peptides in plant proteomes, achieving high classification accuracy and identifying previously unannotated candidates.

This paper benchmarks five scRNA-seq analysis frameworks on scalability, efficiency, and accuracy using large and small datasets, finding GPU acceleration and optimized algorithms improve performance.

The paper develops an AI model to predict successful genomic DNA sequencing from herbarium specimens using morphological, metadata, and DNA quantity features.

This paper introduces Signature Distance, a statistical distance that improves upon energy distance for comparing empirical distributions in high-dimensional biological data, showing greater sensitivity to density changes and enabling model-free data expansion.

This study shows miR-210 is essential for retinal homeostasis in fruit flies and mice, with distinct mechanisms in each species.

This study identifies PAK6 as a positive regulator of neuronal autophagy through TFEB nuclear translocation, with implications for neurodegenerative disease treatment.

The paper shows that low-dose rate γ-irradiation reduces chromosome breaks and telomere fusions in Drosophila by modulating Loquacious expression.

BrewerIX analyzes allelic expression of imprinted and X-linked genes from bulk and single-cell transcriptomes to identify aberrant expression patterns in various biological contexts.

The paper identifies a species-specific retrotransposon promoter that generates a conserved Cdk2ap1 isoform essential for preimplantation development across mammals.

This study shows TGS1 is essential for snRNA 3' end processing and its loss causes neurodegeneration, which can be mitigated by human TGS1 expression in model organisms.