Patricio E. Ray

The paper identifies inflammatory proteolysis of APOL1 in podocytes from HIVAN patients, generating toxic fragments with distinct pathogenic functions.

This paper introduces a Drosophila model to study HIV-1 Nef and APOL1-G1 interaction, showing they synergistically induce ER stress and nephrocyte cell death.

This study shows that Notch3 deletion reduces HIV-1 gene expression and systemic inflammation, improving outcomes in HIV-associated chronic kidney disease.