Tao Li

Pre-myelinating oligodendrocyte ADGRG1 is required for axon ensheathment and CNS myelin formation

This study identifies ADGRG1 as a key regulator of pre-myelinating oligodendrocyte development and axon ensheathment, showing its role in CNS myelin formation through RhoA activation.

Adhesion G protein-coupled receptor ADGRG1 promotes protective microglial response in Alzheimer's disease

This study shows that ADGRG1 in microglia helps protect against Alzheimer's disease by improving amyloid clearance and reducing pathology.

A cross-species proteomic map reveals neoteny of human synapse development

This study creates a cross-species proteomic map of synapse development in human, macaque, and mouse neocortex, revealing slower human PSD maturation and its potential link to neoteny.

A splicing isoform of GPR56 mediates microglial synaptic refinement via phosphatidylserine binding

This study identifies a specific GPR56 splicing isoform that mediates microglial synaptic pruning through phosphatidylserine binding, linking it to neurodevelopmental processes.